On August 15, 2020, an online FAR school dedicated to COVID-19 intensive care practices was held. NANOLEK traditionally supported the event. Three out of five reports covered the topic: "The role and place of extracorporeal treatment methods".
B.V. Silaev, Deputy Chief Physician for Anesthesiology and Resuscitation at the State Clinical Hospital # 15 named after O. M. Filatov, Department of Health of the City of Moscow, emphasized in his report the importance of timely extracorporeal interventions in patients with multiple organ failure caused by COVID-19. Dr. Silaev shared his experience in using "Efferon CT" and "Efferon LPS" columns. All procedures were performed in the "GD + hemoadsorption" cascade mode, sorption columns were in use for not more than 12 hours. Indication for anti-cytokine hemoadsorption were signs of cytokine storm (at PCT<0.5), and for LPS-selective hemoadsorption – diagnosed gram negative sepsis.
S.V. Masolitin, an anesthesiologist-resuscitator, represented the team of contributors on behalf of the State Clinical Hospital # 1 named after N.I. Pirogov, Department of Health of the City of Moscow. Is speech he elaborated on details of pathogenetic reasons for the use of anti-cytokine hemoadsorption in COVID-19 and summarized the experience of using Efferon CT columns in 29 patients with MOF (multiple organ failure) he managed to gather at his department. Early use of Efferon CT could stop progression of MOF, increase the oxygenation index, reduce the concentration of Il-6, and CRP. Dr. Masolitin made specific mention of the protective function of Efferon CT columns and emphasized that none of the self-breathing patients undergoing extracorporeal detoxification were subsequently transferred to a ventilator.
A report delivered by S.R. Gurbanova, transfusiologist of the Department of extracorporeal treatment and detoxification practices at the National Medical Research Center of Obstetrics, Gynecology and Perinatology named after academician V.I. Kulakov, sparked the most lively discussion among more than 1,600 participants of the online school. Dr. Gurbanova told about several complex clinical cases that involved a series of intensive extracorporeal haemocorrection procedures. Dr. Gurbanova expressly indicated the unique properties of Efferon LPS columns, which selectively affect two heterogeneous types of therapeutic targets at the same time (LPS and cytokines), and noted the contribution of these properties to the therapy outcome.
We would like to thank all participants of the event for their interest and attention devoted to the topic and questions asked.
Please do not hesitate to send your questions and inquiries to: efferon@nanolek.ru
